According to current understanding, there are more than 100 components in the cannabis plant. Cannabidiol (CBD) and tetrahydrocannabinol (THC) are two of the most abundant and well-known chemicals present in the plant. Each cannabinoid chemical has its own set of characteristics and may have varied effects on the body.

The most apparent difference is that THC makes you feel nice, while CBD does not. Furthermore, because of legal issues, CBD may only be obtained from the cannabis plant in a limited number of locations.

Hemp and Cannabis

Cannabis and hemp are two distinct varieties of the cannabis plant, each with its own set of rules. Cannabis has a THC content of more than.3 percent, whereas hemp has less than 3 percent THC.

Hemp and cannabis utilize the same endocannabinoid system (ECS) in the human body, which governs their effects. The endocannabinoid system (ECS) is a collection of receptors and endocannabinoids that influence them. These combine to have an influence on a wide range of essential activities, including pain, hunger, sleep, and more.

Cannabis also includes a variety of cannabinoids, terpenes, and flavonoids that may help the body. THC and CBD are by far the most prevalent of these chemicals, with a lot of research done on them. But what are they, how do they function, and why are they different from one another?

CBD and THC – The Superstar Cannabinoids

For a long time, the majority of people associated marijuana with intoxication, so the focus was only on THC. Recently, scientists have identified CBD and other cannabinoids, suggesting that another area of research opens up. Both THC and CBD are cannabinoids found in the cannabis plant. They’re both present in the crystalline resinous trichomes that cover a mature cannabis flower, although each has a distinct concentration.

What is THC & How Does It Work?

Cannabidiol (CBD) is the most prevalent and well-known component in cannabis, and it makes people feel high. A high-THC strain will undoubtedly have an influence on your brain, but it may also offer therapeutic advantages that are sometimes overlooked.

THC activates neurons when it enters your brain, causing dopamine release. THC also activates cannabinoid receptors in the brain, which have a variety of effects. While certain THC strains provide you with a burst of energy and creativity, other strains provide you with a relaxing effect as the high takes over your body. Within 10 minutes after taking particularly potent cannabis, you can experience the following symptoms:

  • Increase in appetite
  • Drowsiness
  • Analgesic
  • Relaxation
  • Euphoria

What is CBD & How Does It Work?

Cannabidiol (CBD) is a non-intoxicating cannabinoid that’s often used to treat illnesses since there is no “high” associated with it. While researchers continue to examine how CBD works in the body, studies show that it interacts with the ECS. CB1 and CB2 are two of the main cannabinoid receptors found in the ECS. The CB1 receptors are mostly found in the brain and play an important part in memory, sleep, mood, hunger, pain sensation, and other activities.

Cannabidiol (CBD) has two types of receptors: CB1 and CB2. The endocannabinoid system, which includes cannabinoid receptors and endocannabinoids, control pain, inflammation, mood, memory, hunger, pleasure, movement difficulties such as Parkinson’s disease Tremors), depression. THC binds to both kinds of receptors but CBD activates them indirectly by increasing the amount of endocannabinoids in the body. CBD also inhibits natural endocannabinoid breakdown. Here are a handful of CBD’s most typical effects:

  • Anti-anxiety
  • Anti-convulsant
  • Neuroprotective
  • Antioxidant
  • Anti-inflammatory

THC – Why the High?

When it comes to the intoxicating effects of cannabis, we must pay attention to CB1 receptors in the brain and nervous system. THC binds strongly to CB1, whereas CBD does not. Because THC is shaped like a plug – i.e., fits nicely into a CB1 receptor socket – it activates these receptors effectively.

THC, the most common cannabinoid in cannabis, binds specifically to CB1 receptors. Furthermore, it partially mimics the ‘bliss molecule’ known as anandamide, which is a naturally occurring endocannabinoid. The fact that THC resembles anandamide contributes to its euphoric effects.

Cannabidiol (CBD) is an antagonist of CB1 receptors, making it a bad fit. In fact, it inhibits THC’s CB1-activating abilities. CBD, in a nutshell, means that THC’s psychoactive effects will be reduced. If you smoke cannabis with 22% THC content, for example, you may experience dizziness or euphoria. The psychoactive effects and anxiety will both be decreased if the cannabis contains 8% CBD.

CBD vs. THC: Chemical structure

The same chemical structure applies to both CBD and THC: 21 carbon atoms, 30 hydrogen atoms, and two oxygen atoms. The differences in your body’s responses are due to a change in the way the atoms are positioned.

Cannabidiol (CBD) and tetrahydrocannabinol (THC) are chemically similar to your body’s endocannabinoids.

The interaction’s influence on neurotransmitter production in your brain is readily apparent. Neurotransmitters are chemical messengers that link neurons and have functions in a variety of things, including pain, immune function, stress, and sleep.

CBD vs. THC: Psychoactive components

Despite having comparable chemical structures, CBD and THC produce distinct psychotropic effects. CBD is psychoactive, although not in the same way as THC. It doesn’t cause the euphoria associated with THC. CBD has been demonstrated to help reduce anxiety, sadness, and seizures.

The chemical component in cannabis that makes you feel high is tetrahydrocannabinol (THC). THC binds to cannabinoid receptors in the brain, causing a sensation of euphoria. CBD has no affinity for CB1 receptors and cannot bind on its own. In order for CBD to work, THC must bind to CB1 receptors, which can help minimize some of the undesirable psychotropic effects of THC, such as euphoria or lethargy.

CBD vs. THC: Legality

On a regular basis, cannabis-related laws are changing in the United States. CBD, according to federal law, remains a Schedule I substance. Hemp has been removed from the Controlled Substances Act, although CBD is still classified as a Schedule I narcotic by the Drug Enforcement Administration (DEA) and the Food and Drug Administration (FDA).

However, 33 states and the District of Columbia have decriminalized or legalized cannabis-related laws, allowing for medical marijuana with a high THC concentration. Several countries now allow the use of THC and cannabis for recreational purposes. CBD should be able to be obtained in any location where cannabis is legal for both personal and therapeutic usage.

Before attempting to purchase CBD or THC-infused items, you should be aware of your state’s rules. If you have cannabis-related products in a state where they’re prohibited or don’t require a medical prescription, you could face legal difficulties.

CBD vs. THC: Medical benefits

CBD and THC have a lot of medical benefits in common. They can help with a variety of health problems. CBD, on the other hand, does not cause the same euphoric effects as THC. Because to this side effect, some people may prefer CBD over THC because of its lack of intoxicating properties.

In June 2018, the United States Food and Drug Administration (FDA) gave approval to Trusted Source Epidiolex, a medicine composed of CBD. It’s used to treat hard-to-control types of epilepsy that aren’t responsive to other treatments. (Epidiolex is not yet approved for any of the following disorders.)

CBD vs. THC: Side effects

CBD is a relatively safe medication, even when taken in large dosages. According to StudyTrusted Source, any CBD adverse effects are most likely due to interactions between CBD and any other medicines you’re taking.

The following adverse effects are due to the psychotropic properties of the drug. Each is not life-threatening. Marijuana dependence, on the other hand, has been connected to long-term mental issues in a subset of persons. This is especially true for teenagers who consume a lot of THC, but there isn’t enough evidence that cannabis use causes psychiatric disorders such as schizophrenia.

CBD vs. THC: Drug testing

THC and CBD are stored in fat in the body. They might be detected for days or even weeks after using drugs on drug tests. nNot every drug test is able to detect CBD, but there are options that are sensitive to it. Marijuana use may show up on a screening due to chemicals linked to THC; however, not all drug tests can identify cannabinoids like THC and CBD.

Even if you haven’t used cannabis, it might be detected in your urine by a test for both CBD and THC. Even though hemp can create THC as well as CBD, a check for both cannabinoids may come back positive. It’s critical to note that products labeled “THC-free” may not contain no THC.

Cannabinoids are compounds in cannabis that bind to cannabinoid receptors. Cannabinoids are chemicals found in cannabis that interact with cannabinoid receptors. CBD and THC are two of the most well-known cannabinoids in cannabis. Both cannabis and hemp produce CBD and THC. Cannabis contains a greater concentration of THC than hemp, according to a reputable source. The average amount of THC contained in today’s cannabis strains is around 12%. “THC” was claimed by a reliable source.

CBD & THC – Better Together?

When cannabinoids, flavonoids, and terpenes from a cannabis plant are combined, it appears that they perform far better for medical applications than any single component alone. The entourage effect is responsible for this; when cannabis’ components are combined, unexpected benefits can be obtained that no individual component can achieve alone.

Cannabis has the ability to relieve chronic pain in a unique way. THC alone can handle severe suffering effectively, but CBD can assist with anxiety symptoms that may accompany chronic illnesses. The use of CBD for sleep is becoming increasingly popular. A blend of THC, CBD, and terpenes has been shown to help with depression, arthritis, anxiety disorders, and headaches.

Legal Status


Uruguay was the first nation on Earth to legalize marijuana for recreational use in 2014. In Canada, Bill C-45 was passed. This legislation allows individuals to keep up to 30 grams of cannabis. It also permits the establishment of businesses that sell cannabis. Cannabis is illegal at a federal level in the United States. In certain states, however, it is legal for recreational usage.


Cannabidiol (CBD) derived from the cannabis plant is a Schedule I controlled substance. It’s banned across the country, but it may be acquired if the product has less than 0.3 percent THC.

Final Thoughts on CBD Vs. THC

Because of the Farm Bill’s passage, CBD has grown increasingly accessible. CBD goods, such as oils and capsules, are now available to buyers. Early research suggests that CBD may help patients with Parkinson’s disease manage their symptoms. Future studies might show even more about CBD and how it can be utilized.

Mucus, on the other hand, may be helpful for a number of illnesses. CBD, on the other hand, has been discovered to aid with a wide range of ailments. THC, for example, has been linked to better symptom alleviation and prevention in one research.

According to the research, more THC was linked with greater effects, but there was no indication of a link between the amount of CBD and symptom alleviation. Despite THC’s possible advantages, it has a perceptible impact on perception. Its psychoactive profile may be an issue for some people.

While THC and CBD can help with a number of conditions when utilized together, they may also assist with multiple sclerosis. One potential explanation for the effectiveness of whole-plant cannabis is CBD’s ability to counteract THC’s psychotropic effects.

Cannabidiol (CBD) and tetrahydrocannabinol (THC) have medical applications, as do several other cannabinoids. They’re both considered safe, but you should be aware of any possible side effects or drug interactions. Before using it, talk to your doctor or a knowledgeable cannabis or CBD expert to ensure that you understand the risks involved.

When the number of CBD and THC study grows, a deeper knowledge of how each chemical might help people may be more effectively discussed and analyzed.

Leave a Reply